{"product_id":"abm163528","title":"HEXA Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eHEXA encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660555493716,"sku":"ABM163528","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660555526484,"sku":"ABM163529","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660555559252,"sku":"ABM163530","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-7f8c6787f3850b68e1e46ccab34496b3b5f514028d069b74034b6b943d168e73.jpg?v=1792157324","url":"https:\/\/www.abmium.com\/fr\/products\/abm163528","provider":"ABMIUM","version":"1.0","type":"link"}