{"product_id":"abm161413","title":"Filamin 1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eFilamin-A encoded by FLNA is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. Filamin-A is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. Filamin-A interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in FLNA are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659726889300,"sku":"ABM161413","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659726922068,"sku":"ABM161414","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659726954836,"sku":"ABM161415","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-aaf29e3417f498679a0167bc3a294d611d0c406beb318a956d9827f062e0e73f.jpg?v=1792157325","url":"https:\/\/www.abmium.com\/fr\/products\/abm161413","provider":"ABMIUM","version":"1.0","type":"link"}