{"product_id":"abm161059","title":"FADD Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe protein encoded by FADD (Fas associated via death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6\/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10\/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660516270420,"sku":"ABM161059","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660516303188,"sku":"ABM161060","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660516335956,"sku":"ABM161061","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-dff84dab38d71f7e89ed10d21da6eef7d406a249a123d120c0084158c3cb337e.jpg?v=1792157388","url":"https:\/\/www.abmium.com\/fr\/products\/abm161059","provider":"ABMIUM","version":"1.0","type":"link"}