{"product_id":"abm158119","title":"COX11 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. COX11 encodes COX11, cytochrome c oxidase copper chaperone which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659971273044,"sku":"ABM158119","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659971305812,"sku":"ABM158120","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659971338580,"sku":"ABM158121","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-ab5596f9dc9ee7785136ad668f4b7b72275b5d7259550b53ce64df6cba83a850.jpg?v=1792157348","url":"https:\/\/www.abmium.com\/fr\/products\/abm158119","provider":"ABMIUM","version":"1.0","type":"link"}