{"product_id":"abm157354","title":"Cleaved-Caspase-4 p20 (Q81) Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eCASP4 encodes caspase 4 that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, CASP4 induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660307112276,"sku":"ABM157354","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660307145044,"sku":"ABM157355","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660307177812,"sku":"ABM157356","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-8bafa049b206fbd91803b97483ef26d64b6bcfd9a917885699aa22983330461e.jpg?v=1792157345","url":"https:\/\/www.abmium.com\/fr\/products\/abm157354","provider":"ABMIUM","version":"1.0","type":"link"}