{"product_id":"abm156948","title":"ChemR23 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe C-X3-C chemokine family is characterized by two cysteines separated by three amino acid residues. Fractalkine is a member of this chemokine family that binds CX3CR1, previously named V28, and chemokine b receptor-like 1 (CMKBRL1) with high affinity, to induce either leukocyte adhesion and migration or chemotactic functions. CX3CR1 functions with CD4 as a co-receptor for the HIV-1 virus envelope protein, and patients homozygous for a variant haplotype of CX3CR1 progress to AIDS more rapidly than those with other haplotypes. Chemokine receptor-like 1 (also designated G protein-coupled receptor DEZ or ChemR23) belongs to the G protein-coupled receptor 1 family. It is an integral membrane protein functioning as a receptor, possibly a chem-otactic peptide receptor. It also acts as a coreceptor for various SIV strains and for a primary HIV-1 strain. ChemR23 is highly expressed in developing osseous and cartilaginous tissue, brain, kidney, gastrointestinal tissues and myeloid tissue, as well as in adult parathyroid glands.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57660026847572,"sku":"ABM156948","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57660026880340,"sku":"ABM156949","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57660026913108,"sku":"ABM156950","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-3009999cb1ff3ba65d954dc87db8c8f5df9a02efde09416103edfb47c85d45e8.jpg?v=1792157307","url":"https:\/\/www.abmium.com\/fr\/products\/abm156948","provider":"ABMIUM","version":"1.0","type":"link"}