{"product_id":"abm154269","title":"BCAR3 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eBreast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. BCAR3 (breast cancer anti-estrogen resistance 3) encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for BCAR3.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659772666196,"sku":"ABM154269","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659772698964,"sku":"ABM154270","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659772731732,"sku":"ABM154271","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-10697a7107e996cae37a6680da7eb79c3efa9105f931d1f7c9e716fb6f2dfc97.jpg?v=1792157380","url":"https:\/\/www.abmium.com\/fr\/products\/abm154269","provider":"ABMIUM","version":"1.0","type":"link"}