{"product_id":"abm153240","title":"Apaf-1 Polyclonal Antibody","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eAPAF1 encodes a cytoplasmic protein that initiates apoptosis. Apoptotic protease-activating factor 1 contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"20ul","offer_id":57659940471124,"sku":"ABM153240","price":69.0,"currency_code":"GBP","in_stock":true},{"title":"50ul","offer_id":57659940503892,"sku":"ABM153241","price":115.0,"currency_code":"GBP","in_stock":true},{"title":"100ul","offer_id":57659940536660,"sku":"ABM153242","price":176.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-bbd301394cde556c2d6036ba90240b6fdd9400c3117417d25b8205ad7dd8e227.jpg?v=1792157357","url":"https:\/\/www.abmium.com\/fr\/products\/abm153240","provider":"ABMIUM","version":"1.0","type":"link"}