{"product_id":"tribio-rocaglamide-tnfa-inhibitor","title":"Rocaglamide, TNFa inhibitor","description":"\u003cp\u003ePotent inhibitor of NFκB in T-lymphocytes with almost complete inhibition at 200 nM. Completely inhibits IL-4 and IFN-γ production and suppresses IL-2 and TNF-α production at 50 nM in T-cells, without inhibiting AP-1 and NF-κB. Immunosuppresive activity is due to inhibition of cytokine gene expression via blocking NF-AT activity. Has anti-cancer properties via various pathways including ERK inhibition, ATM\/ATR-Chk1\/Chk2 activation, and p38 and JNK activation\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"100 µg","offer_id":57411059253588,"sku":"ABM148670-1","price":98.0,"currency_code":"GBP","in_stock":true},{"title":"500 µg","offer_id":57411059286356,"sku":"ABM148670-2","price":392.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI2484.png?v=1791104977","url":"https:\/\/www.abmium.com\/es\/products\/tribio-rocaglamide-tnfa-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}