{"product_id":"tribio-nsc47924-phlp-phosphatase-inhibitor-laminin-inhibitor","title":"NSC47924, PHLP phosphatase inhibitor \/ Laminin inhibitor","description":"\u003cp\u003eA potent inhibitor of the Leucine-rich repeat protein phosphatase (PHLPP) an enzyme which is a negative regulator of Akt and PKC (IC50=4 μM). Increases AKT signaling in cells and prevents apoptosis. Also inhibits the 67 kDa laminin receptor (LR) interaction with laminin (LM) and selectively blocks LR-293 cell adhesion to LM IC 50 =19.35 μM) impairing cell migration and invasion. Affects 37\/67 kDa LR cell surface localization and interaction with cellular prion protein\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410938929492,"sku":"ABM147462-1","price":363.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410938962260,"sku":"ABM147462-2","price":109.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1562.png?v=1791103994","url":"https:\/\/www.abmium.com\/es\/products\/tribio-nsc47924-phlp-phosphatase-inhibitor-laminin-inhibitor","provider":"ABMIUM","version":"1.0","type":"link"}