{"product_id":"tribio-cisplatin-anticancer-agent","title":"Cisplatin, Anticancer agent","description":"\u003cp\u003eInduces intra- and interstrand DNA adducts which poison topoisomerase I. Synergizes with topoisomerase I inhibitors such as topotecan. Induces apoptosis by sequential activation of caspase-8, -3 and -6 in osteosarcoma cells. Inhibits expression of X-linked inhibitor of apoptosis protein (XIAP) in human LNCaP cells. Numerous mechanisms inhibit propagation of cisplatin-induced DNA damage to signal apoptosis resulting in resistance. Clinically useful anticancer agent\u003c\/p\u003e\n\u003cp\u003eSolutions in distilled water are not stable and must be used within 1 working day. do not store solutions\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"100 MG","offer_id":57410897084756,"sku":"ABM146829-1","price":82.0,"currency_code":"GBP","in_stock":true},{"title":"500 MG","offer_id":57410897117524,"sku":"ABM146829-2","price":327.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI2204-1.png?v=1791103437","url":"https:\/\/www.abmium.com\/es\/products\/tribio-cisplatin-anticancer-agent","provider":"ABMIUM","version":"1.0","type":"link"}