{"product_id":"tribio-brd-7389-p90-rsk-inhibitor-increases-insulin-expression","title":"BRD-7389, p90 RSK inhibitor; Increases insulin expression","description":"\u003cp\u003eInhibits p90 ribosomal S6 kinase (RSK), IC50 = 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively. Induces a beta-cell-like state in pancreatic apha-cells and induces insulin expression. Increases the endocrine cell content and function of donor human pancreatic islets in culture. Blocks muscarinic acetylcholine receptor-stimulated RSK activation and subsequent proliferation of SNU-407 colon cancer cells\u003c\/p\u003e","brand":"TriBio Science","offers":[{"title":"25 MG","offer_id":57410884272468,"sku":"ABM146743-1","price":458.0,"currency_code":"GBP","in_stock":true},{"title":"5 MG","offer_id":57410884305236,"sku":"ABM146743-2","price":114.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/TBI1424.png?v=1791103405","url":"https:\/\/www.abmium.com\/es\/products\/tribio-brd-7389-p90-rsk-inhibitor-increases-insulin-expression","provider":"ABMIUM","version":"1.0","type":"link"}