{"product_id":"reed-biotech-splicing-factor-1-polyclonal-antibody-ra29999","title":"Splicing factor 1 Polyclonal Antibody","description":"\u003cp\u003esplicing factor 1(SF1) Homo sapiens This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3\u0026amp;apos; splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57251049963860,"sku":"ABM5034393-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57251049996628,"sku":"ABM5034393-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_b72977ae-1968-4a1a-9355-c9058fc00e22.webp?v=1790235234","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-splicing-factor-1-polyclonal-antibody-ra29999","provider":"ABMIUM","version":"1.0","type":"link"}