{"product_id":"reed-biotech-smad7-acetyl-lys70-rabbit-polyclonal-antibody-ra29905","title":"Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody","description":"\u003cp\u003eSMAD family member 7(SMAD7) Homo sapiens The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250430419284,"sku":"ABM5034299-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250430452052,"sku":"ABM5034299-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_7ac982ee-dee0-4fb0-87b5-6c783054761e.webp?v=1790235203","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-smad7-acetyl-lys70-rabbit-polyclonal-antibody-ra29905","provider":"ABMIUM","version":"1.0","type":"link"}