{"product_id":"reed-biotech-rag-a-b-polyclonal-antibody-ra29241","title":"Rag A\/B Polyclonal Antibody","description":"\u003cp\u003efunction:Involved in the RCC1\/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.,similarity:Belongs to the GTR\/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane.,subunit:Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14.7 kDa protein.,tissue specificity:Ubiquitously expressed with highest levels of expression in skeletal muscle, heart, and brain.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250265301332,"sku":"ABM5033635-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250265334100,"sku":"ABM5033635-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_5cc40828-fd02-44c4-9543-8ccdb8fc1640.webp?v=1790235012","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-rag-a-b-polyclonal-antibody-ra29241","provider":"ABMIUM","version":"1.0","type":"link"}