{"product_id":"reed-biotech-nipbl-polyclonal-antibody-ra33565","title":"NIPBL Polyclonal Antibody","description":"\u003cp\u003eNIPBL, cohesin loading factor(NIPBL) Homo sapiens This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250001682772,"sku":"ABM5037959-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250001715540,"sku":"ABM5037959-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_4061edc1-df44-4777-82c9-bfbc80ad15d3.webp?v=1790234632","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-nipbl-polyclonal-antibody-ra33565","provider":"ABMIUM","version":"1.0","type":"link"}