{"product_id":"reed-biotech-mcm4-polyclonal-antibody-ra27092","title":"MCM4 Polyclonal Antibody","description":"\u003cp\u003eminichromosome maintenance complex component 4(MCM4) Homo sapiens The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC\/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcri\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249660240212,"sku":"ABM5031486-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249660272980,"sku":"ABM5031486-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody_1_300cc9de-74ef-4854-8a21-cbaba4696793.webp?v=1790234455","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-mcm4-polyclonal-antibody-ra27092","provider":"ABMIUM","version":"1.0","type":"link"}