{"product_id":"reed-biotech-fadd-phospho-ser191-polyclonal-antibody-ra24837","title":"FADD (phospho Ser191) Polyclonal Antibody","description":"\u003cp\u003eThe Fas associated via death domain encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6\/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10\/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249887191380,"sku":"ABM5029231-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249887224148,"sku":"ABM5029231-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-fadd-phospho-ser191-polyclonal-antibody-ra24837","provider":"ABMIUM","version":"1.0","type":"link"}