{"product_id":"reed-biotech-eri1-polyclonal-antibody-ra24693","title":"ERI1 Polyclonal Antibody","description":"\u003cp\u003ecofactor:Binds 2 magnesium ions per subunit.,enzyme regulation:Although it can bind simultaneously with SLBP to the 3'-end of histone mRNA, the presence of SLBP prevents the exonuclease activity.,function:RNA exonuclease that binds to the 3'-end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Required for 5.8S rRNA 3'-end processing.,sequence caution:Translated as Leu.,similarity:Contains 1 exonuclease domain.,similarity:Contains 1 SAP domain.,subunit:Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs. Requires the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Binds to 40S and 60S ribosomal subunits and to 80S assembled ribosomes. Also binds to 5.8s ribosomal RNA.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250686697812,"sku":"ABM5029087-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250686730580,"sku":"ABM5029087-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-eri1-polyclonal-antibody-ra24693","provider":"ABMIUM","version":"1.0","type":"link"}