{"product_id":"reed-biotech-dyr1a-polyclonal-antibody-ra32094","title":"DYR1A Polyclonal Antibody","description":"\u003cp\u003edual specificity tyrosine phosphorylation regulated kinase 1A(DYRK1A) Homo sapiens This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine\/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5\u0026amp;apos; UTR or in the 3\u0026amp;apos; co\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250339225940,"sku":"ABM5036488-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250339258708,"sku":"ABM5036488-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-dyr1a-polyclonal-antibody-ra32094","provider":"ABMIUM","version":"1.0","type":"link"}