{"product_id":"reed-biotech-dux4-rabbit-polyclonal-antibody-ra32083","title":"DUX4 Rabbit Polyclonal Antibody","description":"\u003cp\u003eThis gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes; the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250287059284,"sku":"ABM5036477-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250287092052,"sku":"ABM5036477-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-dux4-rabbit-polyclonal-antibody-ra32083","provider":"ABMIUM","version":"1.0","type":"link"}