{"product_id":"reed-biotech-doc-1-polyclonal-antibody-ra24280","title":"DOC-1 Polyclonal Antibody","description":"\u003cp\u003ecyclin dependent kinase 2 associated protein 1(CDK2AP1) Homo sapiens The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha\/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57249891778900,"sku":"ABM5028674-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57249891811668,"sku":"ABM5028674-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-doc-1-polyclonal-antibody-ra24280","provider":"ABMIUM","version":"1.0","type":"link"}