{"product_id":"reed-biotech-crk-ii-phospho-tyr221-polyclonal-antibody-ra23799","title":"Crk II (phospho Tyr221) Polyclonal Antibody","description":"\u003cp\u003eCRK proto-oncogene, adaptor protein(CRK) Homo sapiens This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250349646164,"sku":"ABM5028193-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250349678932,"sku":"ABM5028193-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-crk-ii-phospho-tyr221-polyclonal-antibody-ra23799","provider":"ABMIUM","version":"1.0","type":"link"}