{"product_id":"reed-biotech-c-myc-acetyl-lys148-rabbit-polyclonal-antibody-ra23574","title":"c-Myc (Acetyl Lys148) Rabbit Polyclonal Antibody","description":"\u003cp\u003edisease:A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with BTG1.,disease:Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors.,function:Participates in the regulation of gene transcription. Binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.,online information:Myc entry,PTM:Phosphorylated by PRKDC.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C and SPAG9. Interacts with PARP10. Interacts with KDM5A and KDM5B.,\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250702295380,"sku":"ABM5027968-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250702328148,"sku":"ABM5027968-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-c-myc-acetyl-lys148-rabbit-polyclonal-antibody-ra23574","provider":"ABMIUM","version":"1.0","type":"link"}