{"product_id":"reed-biotech-als2-polyclonal-antibody-ra31071","title":"ALS2 Polyclonal Antibody","description":"\u003cp\u003eALS2, alsin Rho guanine nucleotide exchange factor(ALS2) Homo sapiens The protein encoded by this gene contains an ATS1\/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50 µL","offer_id":57250019770708,"sku":"ABM5035465-1","price":113.4,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":57250019803476,"sku":"ABM5035465-2","price":153.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Antibody.webp?v=1790791467","url":"https:\/\/www.abmium.com\/es\/products\/reed-biotech-als2-polyclonal-antibody-ra31071","provider":"ABMIUM","version":"1.0","type":"link"}