{"product_id":"rabbit-polyclonal-antibody-to-ube2w-p09302","title":"Anti-UBE2W Rabbit Polyclonal Antibody","description":"\u003cp\u003eAccepts ubiquitin from the E1 complex and catalyses its covalent attachment to other proteins. Specifically monoubiquitinates the N-terminus of various substrates, including ATXN3, MAPT\/TAU, POLR2H\/RPB8 and STUB1\/CHIP, by recognizing backbone atoms of disordered N-termini. UBE2W is involved in degradation of misfolded chaperone substrates by mediating monoubiquitination of STUB1\/CHIP, leading to recruitment of ATXN3 to monoubiquitinated STUB1\/CHIP, and restriction of the length of ubiquitin chain attached to STUB1\/CHIP substrates by ATXN3.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006931505492,"sku":"ABM404683-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006931538260,"sku":"ABM404683-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006931571028,"sku":"ABM404683-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-ube2w-p09302","provider":"ABMIUM","version":"1.0","type":"link"}