{"product_id":"rabbit-polyclonal-antibody-to-traf4-p00757","title":"Anti-TRAF4 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eTRAF4\u003c\/strong\u003e is a adapter protein with E3 ligase activity that is involved in many diverse biological processes including cell proliferation, migration, differentiation, DNA repair, platelet activation or apoptosis. TRAF4 promotes EGFR-mediated signalling by facilitating the dimerization of EGFR and downstream AKT activation thereby promoting cell proliferation. Ubiquitinates SMURF2 through 'Lys-48'-linked ubiquitin chain leading to SMURF2 degradation through the proteasome and subsequently osteogenic differentiation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006405874004,"sku":"ABM401095-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006405906772,"sku":"ABM401095-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006405939540,"sku":"ABM401095-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-traf4-p00757","provider":"ABMIUM","version":"1.0","type":"link"}