{"product_id":"rabbit-polyclonal-antibody-to-tead3-p10095","title":"Anti-TEAD3 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eTEAD3\u003c\/strong\u003e is a transcription factor which plays a key role in the Hippo signalling pathway, a pathway involved in organ size control and tumour suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1\/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1\/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1\/TAZ. TEAD3 acts by mediating gene expression of YAP1 and WWTR1\/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58007048847700,"sku":"ABM405332-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58007048880468,"sku":"ABM405332-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58007048913236,"sku":"ABM405332-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-tead3-p10095","provider":"ABMIUM","version":"1.0","type":"link"}