{"product_id":"rabbit-polyclonal-antibody-to-srgap2-p33293","title":"Anti-SRGAP2 Rabbit Polyclonal Antibody","description":"\u003cp\u003ePostsynaptic RAC1 GTPase activating protein (GAP) that plays a key role in neuronal morphogenesis and migration mainly during development of the cerebral cortex. SRGAP2 regulates excitatory and inhibitory synapse maturation and density in cortical pyramidal neurons. SRGAP2\/SRGAP2A limits excitatory and inhibitory synapse density through its RAC1-specific GTPase activating activity, while it promotes maturation of both excitatory and inhibitory synapses through its ability to bind to the postsynaptic scaffolding protein HOMER1 at excitatory synapses, and the postsynaptic protein GPHN at inhibitory synapses.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58157067469140,"sku":"ABM416196-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58157067501908,"sku":"ABM416196-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58157067534676,"sku":"ABM416196-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-srgap2-p33293","provider":"ABMIUM","version":"1.0","type":"link"}