{"product_id":"rabbit-polyclonal-antibody-to-rnf115-p09025","title":"Anti-RNF115 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eRNF115\u003c\/strong\u003e is an E3 ubiquitin-protein ligase that catalyses the 'Lys-48'- and\/or 'Lys-63'-linked polyubiquitination of various substrates and thereby plays a role in a number of signalling pathways including autophagy, innate immunity, cell proliferation and cell death. RNF115 plays a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET and CXCR4 through their polyubiquitination. RNF115 participates together with BST2 in antiviral immunity by facilitating the internalization of HIV-1 virions into intracellular vesicles leading to their lysosomal degradation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006903718228,"sku":"ABM404460-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006903750996,"sku":"ABM404460-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006903783764,"sku":"ABM404460-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-rnf115-p09025","provider":"ABMIUM","version":"1.0","type":"link"}