{"product_id":"rabbit-polyclonal-antibody-to-pim3-p42940","title":"Anti-PIM3 Rabbit Polyclonal Antibody","description":"\u003cp\u003eProto-oncogene with serine\/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. PIM3 may contribute to tumorigenesis through: the delivery of survival signalling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1\/3 (ERK1\/2), through SOCS6.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58167113056596,"sku":"ABM419911-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58167113089364,"sku":"ABM419911-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58167113122132,"sku":"ABM419911-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-pim3-p42940","provider":"ABMIUM","version":"1.0","type":"link"}