{"product_id":"rabbit-polyclonal-antibody-to-lat-ab-255-p41783","title":"Anti-LAT (Ab-255) Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eLAT\u003c\/strong\u003e is required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signalling, both in mature T-cells and during their development. LAT is involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signalling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signalling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signalling molecules.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58162587533652,"sku":"ABM418903-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58162587566420,"sku":"ABM418903-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58162587599188,"sku":"ABM418903-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-lat-ab-255-p41783","provider":"ABMIUM","version":"1.0","type":"link"}