{"product_id":"rabbit-polyclonal-antibody-to-igfbp2-p05699","title":"Anti-IGFBP2 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eIGFBP2\u003c\/strong\u003e is a multifunctional protein that plays a critical role in regulating the availability of IGFs such as IGF1 and IGF2 to their receptors and thereby regulates IGF-mediated cellular processes including proliferation, differentiation, and apoptosis in a cell-type specific manner. IGFBP2 functions coordinately with receptor protein tyrosine phosphatase beta\/PTPRB and the IGF1 receptor to regulate IGF1-mediated signalling by stimulating the phosphorylation of PTEN leading to its inactivation and AKT1 activation. IGFBP2 plays a positive role in cell migration via interaction with integrin alpha5\/ITGA5 through an RGD motif.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006588916052,"sku":"ABM402483-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006588948820,"sku":"ABM402483-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006588981588,"sku":"ABM402483-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-igfbp2-p05699","provider":"ABMIUM","version":"1.0","type":"link"}