{"product_id":"rabbit-polyclonal-antibody-to-cops5-p00484","title":"Anti-COPS5 Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eCOPS5\u003c\/strong\u003e is thought to function as a protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53\/TP53, c-jun\/JUN, IkappaBalpha\/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006397419860,"sku":"ABM401028-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006397452628,"sku":"ABM401028-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006397485396,"sku":"ABM401028-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-cops5-p00484","provider":"ABMIUM","version":"1.0","type":"link"}