{"product_id":"rabbit-polyclonal-antibody-to-cf150-p34972","title":"Anti-CF150 Rabbit Polyclonal Antibody","description":"\u003cp\u003eNucleotidyltransferase that catalyses the formation of cyclic GMP-AMP (2',3'-cGAMP) from ATP and GTP and plays a key role in innate immunity. Catalysis involves both the formation of a 2',5' phosphodiester linkage at the GpA step and the formation of a 3',5' phosphodiester linkage at the ApG step, producing c[G(2',5')pA(3',5')p]. CGAS acts as a key DNA sensor: directly binds double-stranded DNA (dsDNA), inducing the formation of liquid-like droplets in which CGAS is activated, leading to synthesis of 2',3'-cGAMP, a second messenger that binds to and activates STING1, thereby triggering type-I interferon production.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58161434296660,"sku":"ABM417712-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58161434329428,"sku":"ABM417712-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58161434362196,"sku":"ABM417712-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-cf150-p34972","provider":"ABMIUM","version":"1.0","type":"link"}