{"product_id":"rabbit-polyclonal-antibody-to-cbfb-p09440","title":"Anti-CBFB Rabbit Polyclonal Antibody","description":"\u003cp\u003e\u003cstrong\u003eCBFB\u003c\/strong\u003e forms the heterodimeric complex core-binding factor (CBF) with RUNX family proteins (RUNX1, RUNX2, and RUNX3). RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58006943760724,"sku":"ABM404795-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58006943793492,"sku":"ABM404795-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58006943826260,"sku":"ABM404795-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-cbfb-p09440","provider":"ABMIUM","version":"1.0","type":"link"}