{"product_id":"rabbit-polyclonal-antibody-to-carm1-phospho-ser228-p40299","title":"Anti-CARM1(Phospho-Ser228) Rabbit Polyclonal Antibody","description":"\u003cp\u003eMethylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300\/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activation of transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2\/TCF4 activation, acts synergically with EP300\/P300 and either one of the p160 histone acetyltransferases NCOA1\/SRC1, NCOA2\/GRIP1 and NCOA3\/ACTR or CTNNB1\/beta-catenin to activate transcription.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor research use only.\u003c\/strong\u003e\u003c\/p\u003e","brand":"Promab","offers":[{"title":"50 µL","offer_id":58161928470868,"sku":"ABM418000-1","price":174.2,"currency_code":"GBP","in_stock":true},{"title":"100 µL","offer_id":58161928503636,"sku":"ABM418000-2","price":249.55,"currency_code":"GBP","in_stock":true},{"title":"1 mL","offer_id":58161928536404,"sku":"ABM418000-3","price":1863.52,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/rabbit-polyclonal-antibody-to-carm1-phospho-ser228-p40299","provider":"ABMIUM","version":"1.0","type":"link"}