{"product_id":"proteogenix-recombinant-human-msra-n-his","title":"Recombinant Human MSRA, N-His","description":"\u003ch2\u003eIntroduction to Recombinant Human MSRA\u003c\/h2\u003e \u003cp\u003eRecombinant Human MSRA (methionine sulfoxide reductase A) is a protein that plays a crucial role in maintaining cellular health by repairing oxidative damage to proteins. This protein is derived from a gene found in humans and has been produced in a laboratory setting using recombinant DNA technology. In this article, we will explore the structure, activity, and applications of Recombinant Human MSRA.\u003c\/p\u003e \u003ch2\u003eStructure of Recombinant Human MSRA\u003c\/h2\u003e \u003cp\u003eRecombinant Human MSRA is a 20-kDa protein that consists of 187 amino acids. It is made up of two domains – an N-terminal thioredoxin domain and a C-terminal methionine sulfoxide reductase domain. The N-terminal domain is responsible for reducing disulfide bonds, while the C-terminal domain is responsible for reducing oxidized methionine residues. This unique structure allows Recombinant Human MSRA to effectively repair oxidative damage to proteins.\u003c\/p\u003e \u003ch2\u003eActivity of Recombinant Human MSRA\u003c\/h2\u003e \u003cp\u003eThe main function of Recombinant Human MSRA is to repair oxidized proteins by reducing the sulfoxide form of methionine back to its reduced form. This process is crucial for maintaining the proper function of proteins in the cell. Oxidative damage to proteins can lead to a loss of function, which can have severe consequences for cellular health. Recombinant Human MSRA has been shown to be highly efficient in repairing oxidative damage and restoring protein function.\u003c\/p\u003e \u003cp\u003eIn addition to its role in protein repair, Recombinant Human MSRA also has antioxidant activity. It can scavenge reactive oxygen species (ROS) and protect cells from oxidative stress. This is important because an imbalance between ROS production and antioxidant defense mechanisms can lead to oxidative damage and various diseases.\u003c\/p\u003e \u003ch2\u003eApplications of Recombinant Human MSRA\u003c\/h2\u003e \u003cp\u003eRecombinant Human MSRA has a wide range of applications in both research and therapeutic settings. Its ability to repair oxidative damage to proteins makes it a valuable tool for studying the effects of oxidative stress on cellular function. It has been used in various studies to investigate the role of oxidative stress in diseases such as Alzheimer’s, Parkinson’s, and cardiovascular diseases.\u003c\/p\u003e \u003cp\u003eIn therapeutic applications, Recombinant Human MSRA has shown promising results in treating diseases associated with oxidative stress. For example, studies have shown that it can protect against oxidative damage and improve cardiac function in animal models of heart failure. It has also been shown to have neuroprotective effects in models of Parkinson’s disease.\u003c\/p\u003e \u003cp\u003eRecombinant Human MSRA is also used in the production of vaccines. As an antigen, it has been shown to induce a strong immune response, making it a potential candidate for vaccine development against various diseases.\u003c\/p\u003e \u003ch2\u003eConclusion\u003c\/h2\u003e \u003cp\u003eIn conclusion, Recombinant Human MSRA is a crucial protein that plays a vital role in maintaining cellular health. Its unique structure and activity make it an efficient protein repair enzyme and antioxidant. Its applications in research and therapeutics have shown promising results, making it a valuable tool in the fight against diseases associated with oxidative stress. Further studies on Recombinant Human MSRA and its potential therapeutic applications are needed to fully understand its capabilities and potential benefits.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number ARO-P13020. For research use only.\u003c\/p\u003e\u003cp\u003eHost: Escherichia coli (E.coli); Expression system: Prokaryotic expression; Molecular weight: 25.55 kDa; Fragment: Ala27-Lys235; Buffer: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol..\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/ARO-P13020.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57359120531796,"sku":"ABM143457-1","price":143.2,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57359120564564,"sku":"ABM143457-2","price":207.2,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57359120597332,"sku":"ABM143457-3","price":615.2,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/3d-representation-image-recombinant-human-msra-n-his_f6ecb249-8a3d-41ac-9bb5-721a5b7fde25.webp?v=1790894841","url":"https:\/\/www.abmium.com\/es\/products\/proteogenix-recombinant-human-msra-n-his","provider":"ABMIUM","version":"1.0","type":"link"}