{"product_id":"proteogenix-human-pd-l2-recombinant-protein","title":"Human PD-L2 recombinant protein","description":"\u003ch2\u003eGeneral information on Human PD-L2 recombinant protein\u003c\/h2\u003e Structure \u003cp\u003eHuman PD-L2 recombinant protein is a type I transmembrane glycoprotein and is a member of the B7 family of CD proteins. It consists of a single extracellular immunoglobulin-like domain, a transmembrane domain and a short cytoplasmic tail. \u003c\/p\u003e Activity \u003cp\u003ePD-L2 plays an important role in the regulation of immune responses by binding to its receptor PD-1 on the surface of T cells and B cells. This binding leads to the inhibition of the activation and proliferation of these cells, thus acting as an immune checkpoint protein. \u003c\/p\u003e Application \u003cp\u003eHuman PD-L2 recombinant protein is used in antibody-drug target therapy, where it is used to develop antibodies that can bind to PD-L2 and block the PD-L2\/PD-1 interaction. This can result in the activation and proliferation of T cells and B cells, thus enhancing the immune response against cancer cells.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number PX-P6014. For research use only.\u003c\/p\u003e\u003cp\u003eHost: Mammalian cells; Expression system: Eukaryotic expression; Purity: \u0026gt;85% by SDS-PAGE; Molecular weight: 23.62 kDa; Tag: C-terminal His Tag; Fragment: Met1-Thr220; Buffer: PBS, pH7.5; Applications: ELISA, WB.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/PX-P6014.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/msds\/MSDS_PX-P6014.pdf\"\u003eDownload the manufacturer safety data sheet (MSDS\/SDS)\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"100ug","offer_id":57375949586772,"sku":"ABM145134-1","price":207.2,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/3d-representation-image-human-pd-l2-recombinant-protein.webp?v=1790895723","url":"https:\/\/www.abmium.com\/es\/products\/proteogenix-human-pd-l2-recombinant-protein","provider":"ABMIUM","version":"1.0","type":"link"}