{"product_id":"proteogenix-cd152-recombinant-protein","title":"CD152 Recombinant Protein","description":"\u003ch2\u003eGeneral information on CD152 Recombinant Protein:\u003c\/h2\u003e \u003cp\u003e CD152, also known as CTLA4 and cytotoxic T lymphocyte protein 4, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor. The ligands or counterreceptors of these two proteins belong to the B7, CD8 (B7-1) and CD86 (B7-2) families. CTLA4 delivers inhibitory signals to T lymphocytes, while CD28 delivers stimulatory signals. Intracellular CTLA4 is also present in regulatory T cells and may play an important role in its function. CD152 antigen or cytotoxic T lymphocytes (CTLA-4) are important receptors involved in downregulating T-cell activation. Due to its far-reaching inhibitory effect, CD152 is considered a candidate solid acceptable for autoimmunity and a convincing target for cancer immunotherapy. In particular, recent evidence suggests that CD152 is also important in homeostasis and the function of population suppressor cells called regulatory T cells (Treg).\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number PX-P4108. For research use only.\u003c\/p\u003e\u003cp\u003eHost: Mammalian cells; Expression system: Eukaryotic expression; Purity: \u0026gt;90% by SDS-PAGE; Molecular weight: 18.51kDa; Tag: C-terminal His Tag; Fragment: Met1~Asp161; Buffer: PBS pH7.5; Applications: ELISA, WB.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/PX-P4108.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57376239321428,"sku":"ABM146405-1","price":68.0,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57376239354196,"sku":"ABM146405-2","price":100.0,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57376239386964,"sku":"ABM146405-3","price":303.2,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/bioactivity-validation-cd152-recombinant-protein.jpg?v=1790896802","url":"https:\/\/www.abmium.com\/es\/products\/proteogenix-cd152-recombinant-protein","provider":"ABMIUM","version":"1.0","type":"link"}