{"product_id":"proteogenix-cd102-recombinant-protein","title":"CD102 Recombinant Protein","description":"\u003ch2\u003eGeneral information on CD102 Recombinant Protein:\u003c\/h2\u003e \u003cp\u003e The intercellular adhesion molecule 2 (ICAM-2, CD102) belongs to the ICAM family and consists of three members, which are identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-like domains and binds to the leukocyte integrins LFA-1 (CD11a \/ CD18) and Mac-1 (CD11b \/ CD18). As the second ligand of antigen 1 associated with leukocyte function, ICAM-2 acts as an effective cell costimulatory molecule. ICAM-2 is expressed primarily in vascular endothelial cells and hematopoietic cells. The interaction of ICAM-2 and the integrin receptor mediates cell adhesion of a wide range of lymphocytes, monocytes, natural lethal cells, and granulocytes to other cells, and plays an important role in many immune and inflammatory responses. For example, T lymphocyte aggregation, NK cytotoxic lymphocyte migration, lymphocyte recirculation, etc. ICAM-2 series levels are significantly related to inflammation and trichinosis disease sequence in mice, and have a similar relationship to blood eosinophilia. Therefore, assessing serum ICAM-2 levels can help diagnose a recent trichinosis infection and monitor prognosis and response to treatment.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number PX-P4097. For research use only.\u003c\/p\u003e\u003cp\u003eHost: Mammalian cells; Expression system: Eukaryotic expression; Purity: \u0026gt;90% by SDS-PAGE; Molecular weight: 45kDa; Tag: C-terminal His Tag; Fragment: Met1~Gln223; Buffer: PBS pH7.5; Applications: ELISA, WB.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/PX-P4097.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57376236503380,"sku":"ABM146416-1","price":215.2,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57376236536148,"sku":"ABM146416-2","price":300.0,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57376236568916,"sku":"ABM146416-3","price":884.0,"currency_code":"GBP","in_stock":true}],"url":"https:\/\/www.abmium.com\/es\/products\/proteogenix-cd102-recombinant-protein","provider":"ABMIUM","version":"1.0","type":"link"}