{"product_id":"proteogenix-bevifimod-biosimilar-research-grade","title":"Bevifimod Biosimilar – Research Grade","description":"\u003ch2\u003eBevifimod Biosimilar – Research Grade\u003c\/h2\u003e \u003cp\u003eBevifimod Biosimilar – Research Grade is a recombinant research-use protein designed for studies involving immune modulation, B-cell biology, macrophage activity, and antibody-mediated immune mechanisms. As a biosimilar of bevifimod, also known as PRTX-100, this product supports researchers investigating the biological activity of Staphylococcal protein A and its interaction with immune cell populations involved in inflammatory and autoimmune pathways.\u003c\/p\u003e \u003ch2\u003eBiological Function\u003c\/h2\u003e \u003cp\u003eBevifimod is associated with the selective modulation of immune responses through binding to VH3 immunoglobulin-expressing B cells and macrophage or monocyte populations. This interaction makes it a relevant research target for studying B-cell activation, antibody-mediated signaling, immune complex biology, and macrophage-driven effector functions.\u003c\/p\u003e \u003cp\u003eBy engaging immune cells involved in pathogenic antibody responses, bevifimod is commonly studied in experimental models exploring immune regulation, inflammatory signaling, and mechanisms linked to autoimmune disease biology.\u003c\/p\u003e \u003ch2\u003eMain Research Applications\u003c\/h2\u003e \u003cp\u003eBevifimod Biosimilar – Research Grade is suitable for in vitro and preclinical research applications focused on immune cell modulation and antibody-related mechanisms. It may be used to support studies in autoimmune disease research, immune thrombocytopenia research, rheumatoid arthritis-related models, B-cell response analysis, and macrophage or monocyte functional assays.\u003c\/p\u003e \u003cp\u003eThis product can also be used as a reference protein or research reagent for assay development, target validation, comparative biosimilar studies, and screening workflows involving immune-mediated inflammation.\u003c\/p\u003e \u003ch2\u003eExperimental Use Cases\u003c\/h2\u003e \u003cp\u003eResearchers may use Bevifimod Biosimilar – Research Grade in PBMC-based assays, B-cell activation studies, monocyte or macrophage response assays, and antibody-mediated phagocytosis models. It is also relevant for investigating VH3-related immunoglobulin interactions, immune signaling modulation, and cellular mechanisms involved in platelet destruction or inflammatory immune responses.\u003c\/p\u003e \u003cp\u003eIts research-grade format makes it a practical tool for laboratories evaluating bevifimod-related biology, developing immune-focused assays, or comparing protein activity in controlled experimental settings.\u003c\/p\u003e \u003ch2\u003eFor Research Use Only\u003c\/h2\u003e \u003cp\u003eBevifimod Biosimilar – Research Grade is intended exclusively for research applications. It is not intended for diagnostic, clinical, or therapeutic use.\u003c\/p\u003e\u003cp\u003eProteoGenix catalogue number PX-TA2531.\u003c\/p\u003e\u003cp\u003eTarget: Bevifimod Biosimilar – Research Grade; Host: Mammalian cells; Clonality: Monoclonal antibody; Expression system: Mammalian; Purity: \u0026gt;95% as determined by SDS-PAGE.; Buffer: 0.01M PBS pH 7.4.\u003c\/p\u003e\u003cp\u003eAvailable configurations: 50ug, 100ug, 1mg.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.proteogenix.science\/wp-content\/uploads\/documents\/Datasheets\/PX-TA2531-100.pdf\"\u003eDownload the manufacturer datasheet\u003c\/a\u003e\u003c\/p\u003e","brand":"ProteoGenix","offers":[{"title":"50ug","offer_id":57357569884500,"sku":"ABM133546-1","price":111.2,"currency_code":"GBP","in_stock":true},{"title":"100ug","offer_id":57357569917268,"sku":"ABM133546-2","price":172.0,"currency_code":"GBP","in_stock":true},{"title":"1mg","offer_id":57357569950036,"sku":"ABM133546-3","price":375.2,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/Otherproducts-DNib4svC_86483588-ad14-4556-98e3-3cfd59e1e1c9.svg?v=1790890713","url":"https:\/\/www.abmium.com\/es\/products\/proteogenix-bevifimod-biosimilar-research-grade","provider":"ABMIUM","version":"1.0","type":"link"}