{"product_id":"mouse-cd73-nt5e-elisa-kit-picokine-ek2131","title":"Mouse CD73\/NT5E ELISA Kit PicoKine®","description":"\u003cp\u003eMouse CD73\/NT5E ELISA Kit PicoKine® is a research-use ELISA kit from Boster Bio for measuring 5'-nucleotidase in Cell culture supernatant, serum and plasma (heparin, EDTA) samples from Mouse. Use the listed assay range, sample guidance and protocol documents to assess suitability for the intended study.\u003c\/p\u003e\nMouse CD73\/NT5E ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Nt5e in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 20 pg\/ml. The brand Picokine indicates this is a premium quality ELISA kit. Each Picokine kit delivers precise quantification, high sensitivity, and excellent reproducibility. Only our most reliable and effective kits qualify as Picokine, guaranteeing top-tier results for your assays.\u003cp\u003e5'-nucleotidase (5'-NT), also known as ecto-5'-nucleotidase or CD73 (Cluster of Differentiation 73), is an enzyme that in humans is encoded by the NT5E gene. Ecto-5-prime-nucleotidase catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. And the enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. Rareallelic variants are associated with a syndrome of adult-onset calcification of joints and arteries (CALJA) affecting the iliac, femoral, and tibial arteries reducing circulation in the legs and the joints of the hands and feet causing pain.\u003c\/p\u003e\u003ch3\u003eProduct information\u003c\/h3\u003e","brand":"Boster Bio","offers":[{"title":"96 wells\/kit, with removable strips.","offer_id":56042498326868,"sku":"ABM33673","price":375.7,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/ek2131.png?v=1781657712","url":"https:\/\/www.abmium.com\/es\/products\/mouse-cd73-nt5e-elisa-kit-picokine-ek2131","provider":"ABMIUM","version":"1.0","type":"link"}