{"product_id":"elk-em1058-myosin-heavy-chain-mouse-mab","title":"Myosin Heavy Chain Mouse mAb","description":"\u003cp\u003eMyosin Heavy Chain Mouse mAb is a research-use antibody from ELK Biotechnology for studying Myosin Heavy Chain in IHC, IF workflows with listed reactivity for Human, Mouse, Rat, Fruit fly, Nematode. Specifications and supporting documents below should be reviewed when planning the experiment.\u003c\/p\u003e\n\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMuscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.\u003c\/p\u003e\u003ch3\u003eAdditional antibody information\u003c\/h3\u003e\u003ctable\u003e\u003ctbody\u003e\u003ctr\u003e\n\u003cth\u003eValidation evidence captions\u003c\/th\u003e\n\u003ctd\u003eImmunofluorescence Staining of nematode tissue with MYH mouse mAb(11C2) diluted at 1:100. (Provide by Tsinghua University). | Immunofluorescence double Staining of fruit fly tissue with MYH mouse mAb(11C2)(Green) and F-actin mouse mAb(red) (Provide by NIBS).\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\u003c\/table\u003e","brand":"ELK Biotechnology","offers":[{"title":"Unconjugated \/ 100µL","offer_id":56184863621460,"sku":"ABM102280","price":176.0,"currency_code":"GBP","in_stock":true},{"title":"Unconjugated \/ 50µL","offer_id":56184863654228,"sku":"ABM92416","price":105.6,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/EM1058-c-1.jpg?v=1782026760","url":"https:\/\/www.abmium.com\/es\/products\/elk-em1058-myosin-heavy-chain-mouse-mab","provider":"ABMIUM","version":"1.0","type":"link"}