{"product_id":"abm218144","title":"Human Zinc Finger Protein Gli1, GLI1 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eActs as a transcriptional activator (PubMed: 19706761, PubMed: 10806483, PubMed: 19878745, PubMed: 24311597, PubMed: 24217340). Binds to the DNA consensus sequence 5'-GACCACCCA-3' (PubMed: 2105456, PubMed: 8378770, PubMed: 24217340). Regulates the transcription of specific genes during normal development (PubMed: 19706761). Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling (PubMed: 19706761, PubMed: 28973407). Plays a role in cell proliferation and differentiation via its role in SHH signaling (PubMed: 11238441, PubMed: 28973407). [Isoform 2]: Acts as a transcriptional activator, but activates a different set of genes than isoform 1. Activates expression of CD24, unlike isoform 1. Mediates SHH signaling. Promotes cancer cell migration.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57662093066580,"sku":"ABM218144","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57662093099348,"sku":"ABM218145","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-4c55777d81647626900576fdc3eb62b469bddfbbb5cc05a430a8f62e59d9b567.jpg?v=1792159241","url":"https:\/\/www.abmium.com\/es\/products\/abm218144","provider":"ABMIUM","version":"1.0","type":"link"}