{"product_id":"abm213104","title":"Mouse Ras-related Protein Rab-1A, RAB1A ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eThe small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:20639577, PubMed:22854043). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:20639577, PubMed:22854043). RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion (By similarity). Regulates the level of CASR present at the cell membrane (By similarity). Plays a role in cell adhesion and cell migration, via its role in protein trafficking (PubMed:20639577). Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria (By similarity). Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport (PubMed:22854043).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661658693972,"sku":"ABM213104","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661658726740,"sku":"ABM213105","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-9b07df11761a82f8a6c0a3e2408e7d51d971c7900b4499779386d4ddaa495ca2.jpg?v=1792159227","url":"https:\/\/www.abmium.com\/es\/products\/abm213104","provider":"ABMIUM","version":"1.0","type":"link"}