{"product_id":"abm212588","title":"Rat Thioredoxin-interacting Protein, TXNIP ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eMay act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) (By similarity). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0\/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661772366164,"sku":"ABM212588","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661772398932,"sku":"ABM212589","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-7a9fb1bc83a8963e91b9b5a2356a74a7d61843475e7524c27eae46d735ebf790.jpg?v=1792159244","url":"https:\/\/www.abmium.com\/es\/products\/abm212588","provider":"ABMIUM","version":"1.0","type":"link"}