{"product_id":"abm209616","title":"Human Atrial Natriuretic Peptide-converting Enzyme, CORIN ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eSerine-type endopeptidase involved in atrial natriuretic peptide (NPPA) and brain natriuretic peptide (NPPB) processing (PubMed:10880574, PubMed:21288900, PubMed:20489134, PubMed:21763278). Converts through proteolytic cleavage the non-functional propeptides NPPA and NPPB into their active hormones, ANP and BNP(1-32) respectively, thereby regulating blood pressure in the heart and promoting natriuresis, diuresis and vasodilation (PubMed:10880574, PubMed:21288900, PubMed:20489134, PubMed:21763278). Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus (PubMed:22437503). Also acts as a regulator of sodium reabsorption in kidney (By similarity). has weaker endopeptidase activity compared to isoform 1.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661997547860,"sku":"ABM209616","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661997580628,"sku":"ABM209617","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-62bbd9415da48c35ee53e7dddd981c170cc2bc4bc020ff71a9facfd301f09739.jpg?v=1792159224","url":"https:\/\/www.abmium.com\/es\/products\/abm209616","provider":"ABMIUM","version":"1.0","type":"link"}