{"product_id":"abm208948","title":"Porcine Scavenger Receptor Cysteine-rich Type 1 Protein M130, CD163 ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eInvolved in clearance and endocytosis of hemoglobin\/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin\/haptoglobin and subsequent breakdown of heme. Binds hemoglobin\/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity). May play a role in the process of infection of porcine monocytes\/macrophages by African swine fever virus (ASFV). In case of porcine reproductive and respiratory syndrome virus (PRRSV), serves mediates virion attachment and plays a role in viral entry. After shedding, the soluble form (sCD163) may play an anti-inflammatory role.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661910778196,"sku":"ABM208948","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661910810964,"sku":"ABM208949","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-5a779b361bccde5d8ecb293900d3065161859938b6b6dd2892ad294368c46d31.jpg?v=1792159221","url":"https:\/\/www.abmium.com\/es\/products\/abm208948","provider":"ABMIUM","version":"1.0","type":"link"}