{"product_id":"abm208622","title":"Rabbit Podocalyxin, PCX ELISA Kit","description":"\u003ch3\u003eBackground\u003c\/h3\u003e\u003cp\u003eInvolved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"48T","offer_id":57661665182036,"sku":"ABM208622","price":205.0,"currency_code":"GBP","in_stock":true},{"title":"96T","offer_id":57661665214804,"sku":"ABM208623","price":293.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/1782\/2036\/files\/btlab-9f9dc8143712082968422dc2f7c4698ed8e3363e8d8e826b5474714b559361d7.jpg?v=1792159168","url":"https:\/\/www.abmium.com\/es\/products\/abm208622","provider":"ABMIUM","version":"1.0","type":"link"}